Cusabio N-terminal 10xHis-HA-tagged Recombinant

What is an HA tag? An HA tag is derived from the human influenza hemagglutinin (HA) molecule corresponding to amino acids 98-106. It has been widely used as a general epitope tag in expression vectors. The HA tag does not appear to interfere with the bioactivity or biodistribution of the recombinant HA-tagged protein. What are … Read more

Cusabio Homo sapiens Recombinant

General description: The species to which you and all other living human beings on this planet belong is Homo sapiens Recombinant. During a time of dramatic climate change 300,000 years ago, Homo sapiens evolved in Africa. Like other early humans who lived at this time, they gathered and hunted for food and developed behaviours that … Read more

Cusabio N-terminal 6xHis-Trx-tagged Recombinant

Product name N-terminus 6xHis-Trx-tag, negative control Full product name N-terminal tag 6xHis-Trx For research use only For research use only. It should not be used in diagnostic procedures. Host: E. coli ISO certification Manufactured in an ISO 9001:2015 certified laboratory. Alternative name: TRX Recommended dilutions/conditions: Activity assay (>300U/mg) Western Blot (100 ng, colourimetric) Suggested dilutions/conditions … Read more

Small Non-coding RNAs Are Dysregulated in Huntington’s Disease Transgenic Mice Independently of the Therapeutic Effects of an Environmental Intervention

Small Non-coding RNAs Are Dysregulated in Huntington's Disease Transgenic Mice Independently of the Therapeutic Effects of an Environmental Intervention

Huntington’s illness (HD) is a neurodegenerative dysfunction brought on by a trinucleotide repeat enlargement in the huntingtin gene. Transcriptomic dysregulations are well-documented in HD and alterations in small non-coding RNAs (sncRNAs), notably microRNAs (miRNAs), may underpin that phenomenon. Additionally, environmental enrichment (EE), which is used to mannequin a stimulating way of life in pre-clinical analysis, … Read more

Of rodents and ruminants: a comparison of small noncoding RNA requirements in mouse and bovine reproduction

Of rodents and ruminants: a comparison of small noncoding RNA requirements in mouse and bovine reproduction

Ruminants are main producers of meat and milk, thus managing their reproductive potential is a key ingredient in cost-effective, protected, and environment friendly meals manufacturing. Of explicit concern, defects in male germ cells and feminine germ cells might result in considerably lowered reside births relative to fertilization. However, the underlying molecular drivers of these defects … Read more

A Novel Small RNA Promotes Motility and Virulence of Enterohemorrhagic Escherichia coli O157:H7 in Response to Ammonium

A Novel Small RNA Promotes Motility and Virulence of Enterohemorrhagic Escherichia coli O157:H7 in Response to Ammonium

Enterohemorrhagic Escherichia coli serotype O157:H7 (O157) is a crucial, foodborne, human intestinal pathogen that causes extreme acute hemorrhagic diarrhea, belly cramping, and even loss of life. Small RNAs (sRNAs) are noncoding regulatory molecules that sense environmental adjustments and set off numerous virulence-related signaling pathways; nonetheless, few such sRNAs have been recognized in O157. Here, we report a … Read more

[Novel vector preS1-tp fusion protein effectively inhibits hepatitis B virus replication and cccDNA synthesis by mediating hepatitis B virus targeting sequence small interfering RNA]

[Novel vector preS1-tp fusion protein effectively inhibits hepatitis B virus replication and cccDNA synthesis by mediating hepatitis B virus targeting sequence small interfering RNA]

To research the usage of preS1-tp fusion protein as a novel vector to mediate the entry of small interfering RNA (siRNA) targeting the carboxy-terminal nuclear localization sign (NLS) area of hepatitis B virus (HBV) core protein into HBV-infected hepatocytes, and to additional discover the HBV replication inhibition and covalently closed round DNA synthesis. HepG2.2.15 cells … Read more

Global profile of tRNA-derived small RNAs in gastric cancer patient plasma and identification of tRF-33-P4R8YP9LON4VDP as a new tumor suppressor

Global profile of tRNA-derived small RNAs in gastric cancer patient plasma and identification of tRF-33-P4R8YP9LON4VDP as a new tumor suppressor

Transfer RNA (tRNA)-derived small RNAs (tsRNAs) have been discovered to play vital roles in the incidence and improvement of cancers. However, the tsRNA profile in gastric cancer is unknown. In this examine, we aimed to determine the worldwide tsRNA profile in plasma from gastric cancer sufferers and elucidate the function of tRF-33-P4R8YP9LON4VDP in gastric cancer. … Read more