A Novel Small RNA Promotes Motility and Virulence of Enterohemorrhagic Escherichia coli O157:H7 in Response to Ammonium

Enterohemorrhagic Escherichia coli serotype O157:H7 (O157) is a crucial, foodborne, human intestinal pathogen that causes extreme acute hemorrhagic diarrhea, belly cramping, and even loss of life. Small RNAs (sRNAs) are noncoding regulatory molecules that sense environmental adjustments and set off numerous virulence-related signaling pathways; nonetheless, few such sRNAs have been recognized in O157. Here, we report a novel sRNA, EsrF that senses excessive ammonium concentrations in the colon and enhances O157 pathogenicity by selling bacterial motility and adhesion to host cells.

Specifically, EsrF was discovered to instantly work together with the 5′ untranslated areas of the flagellar biosynthetic gene, flhB, mRNA and improve its abundance, thereby upregulating expression of important flagellar genes, together with flhDflhCfliA, and fliC, main to elevated O157 motility and virulence. Meanwhile, an toddler rabbit mannequin of O157 an infection confirmed that deletion of esrF and flhB considerably attenuates O157 pathogenicity.

Furthermore, NtrC-the response regulator of the NtrC/B two-component system-was discovered to exert direct, damaging regulation of esrF expression. Meanwhile, excessive ammonium concentrations in the colon launch the inhibitory impact of NtrC on esrF, thereby enhancing its expression and subsequently selling bacterial colonization in the host colon. Our work reveals a novel, sRNA-centered, virulence-related signaling pathway in O157 that senses excessive ammonium concentrations. These findings present novel insights for future analysis on O157 pathogenesis and focused therapy methods.

The course of by which micro organism sense environmental cues to regulate their virulence is advanced. Several research have centered on regulating the expression of the locus of enterocyte effacement pathogenicity island in the everyday intestine pathogenic bacterium, O157. However, few investigations have addressed the regulation of different virulence elements in response to intestinal indicators. In this research, we report our discovery of a novel O157 sRNA, EsrF, and show that it contributed to bacterial motility and virulence in vitro and in vivo by the regulation of bacterial flagellar synthesis.

Furthermore, we present that top ammonium concentrations in the colon induced esrF expression to promote bacterial virulence by releasing the repression of esrF by NtrC. This research highlights the significance of sRNA in regulating the motility and pathogenicity of O157.  In this research, carboxyalkylated-PEI25 (25 kDa) was used to ship plasmids expressing SALL4-siRNA into MCF-7 cells. DLS and AFM had been utilized to decide the dimensions of nanoparticles. The MTT technique was used to assess cytotoxicity, and the effectivity of transfection was confirmed each qualitatively and quantitatively. Finally, the impact of silencing SALL4 was investigated on the migration of MCF7 cells utilizing the scratch check.

Polyploidy-associated paramutation in Arabidopsis is set by small RNAs, temperature, and allele construction

Paramutation is a kind of non-Mendelian inheritance in which the expression of a paramutable allele adjustments when it encounters a paramutagenic allele. This change in expression of the paramutable alleles is stably inherited even after segregation of each alleles. While the invention of paramutation and research of its underlying mechanism had been made with alleles that change plant pigmentation, paramutation-like phenomena are recognized to modulate the expression of different traits and in different eukaryotes, and many instances have most likely gone undetected.

It is probably going that epigenetic mechanisms are accountable for the phenomenon, as paramutation types epialleles, genes with similar sequences however totally different expression states. This might account for the intergenerational inheritance of the paramutated allele, offering profound proof that triggered epigenetic adjustments will be maintained over generations. Here, we use a case of paramutation that impacts a transgenic choice reporter gene in tetraploid Arabidopsis thaliana. Our information counsel that differing types of small RNA are derived from paramutable and paramutagenic epialleles.

In addition, deletion of a repeat inside the epiallele adjustments its paramutability. Further, the temperature through the progress of the epiallelic hybrids determines the diploma and timing of the allelic interplay. The information additional make it believable why paramutation in this method turns into evident solely in the segregating F2 inhabitants of tetraploid vegetation containing each epialleles. In abstract, the outcomes help a mannequin for polyploidy-associated paramutation, with similarities in addition to distinctions from different instances of paramutation.

A Novel Small RNA Promotes Motility and Virulence of Enterohemorrhagic Escherichia coli O157:H7 in Response to Ammonium

A artificial small molecule stalls pre-mRNA splicing by selling an early-stage U2AF2-RNA advanced

Dysregulated pre-mRNA splicing is an rising Achilles heel of cancers and myelodysplasias. To develop the at present restricted portfolio of small-molecule drug leads, we screened for chemical modulators of the U2AF advanced, which nucleates spliceosome meeting and is mutated in myelodysplasias. A hit compound particularly enhances RNA binding by a U2AF2 subunit. Remarkably, the compound inhibits splicing of consultant substrates and stalls spliceosome meeting on the stage of U2AF perform. Computational docking, along with structure-guided mutagenesis, signifies that the compound bridges the tandem U2AF2 RNA recognition motifs through hydrophobic and electrostatic moieties. Cells expressing a cancer-associated

Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) Antibody

abx238835-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) Antibody

20-abx001574
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

ELISA kit for Rat Troponin C, slow skeletal and cardiac muscles (TNNC1)

KTE101020-48T 48T
EUR 332
  • Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase
  • TnT, which contains the bindi
  • Show more
Description: Quantitative sandwich ELISA for measuring Rat Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Troponin C, slow skeletal and cardiac muscles (TNNC1)

KTE101020-5platesof96wells 5 plates of 96 wells
EUR 2115
  • Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase
  • TnT, which contains the bindi
  • Show more
Description: Quantitative sandwich ELISA for measuring Rat Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Troponin C, slow skeletal and cardiac muscles (TNNC1)

KTE101020-96T 96T
EUR 539
  • Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase
  • TnT, which contains the bindi
  • Show more
Description: Quantitative sandwich ELISA for measuring Rat Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Bovine Troponin C, slow skeletal and cardiac muscles, TNNC1 ELIS

ELI-17222b 96 Tests
EUR 928

Mouse Troponin C, slow skeletal and cardiac muscles, Tnnc1 ELISA

ELI-36461m 96 Tests
EUR 865

Porcine Troponin C, slow skeletal and cardiac muscles, TNNC1 ELI

ELI-39993p 96 Tests
EUR 928

Human Troponin C, slow skeletal and cardiac muscles, TNNC1 ELISA

ELI-40072h 96 Tests
EUR 824

Human Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) ELISA Kit

20-abx153332
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

ELISA kit for Human Troponin C, slow skeletal and cardiac muscles

EK3670 96 tests
EUR 670
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Troponin C, slow skeletal and cardiac muscles in samples from serum, plasma, tissue homogenates and other biological fluids.

Human TNNC1/ Troponin C, slow skeletal and cardiac muscles ELISA Kit

E2558Hu 1 Kit
EUR 605

Human Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) ELISA Kit

abx352187-96tests 96 tests
EUR 786
  • Shipped within 5-12 working days.

Chicken Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) ELISA Kit

abx555347-96tests 96 tests
EUR 911
  • Shipped within 5-12 working days.

Human Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) ELISA Kit

abx555435-96tests 96 tests
EUR 786
  • Shipped within 5-12 working days.

Mouse Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) ELISA Kit

abx555608-96tests 96 tests
EUR 739
  • Shipped within 5-12 working days.

Pig Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) ELISA Kit

abx555672-96tests 96 tests
EUR 911
  • Shipped within 5-12 working days.

Cow Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) ELISA Kit

abx555769-96tests 96 tests
EUR 911
  • Shipped within 5-12 working days.

ELISA kit for Chicken Troponin C, slow skeletal and cardiac muscles (TNNC1)

KTE30009-48T 48T
EUR 354
  • Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase
  • TnT, which contains the bindi
  • Show more
Description: Quantitative sandwich ELISA for measuring Chicken Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Chicken Troponin C, slow skeletal and cardiac muscles (TNNC1)

KTE30009-5platesof96wells 5 plates of 96 wells
EUR 2252
  • Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase
  • TnT, which contains the bindi
  • Show more
Description: Quantitative sandwich ELISA for measuring Chicken Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Chicken Troponin C, slow skeletal and cardiac muscles (TNNC1)

KTE30009-96T 96T
EUR 572
  • Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase
  • TnT, which contains the bindi
  • Show more
Description: Quantitative sandwich ELISA for measuring Chicken Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Goat Troponin C, slow skeletal and cardiac muscles (TNNC6)

KTE50026-48T 48T
EUR 425
Description: Quantitative sandwich ELISA for measuring Goat Troponin C, slow skeletal and cardiac muscles (TNNC6) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Goat Troponin C, slow skeletal and cardiac muscles (TNNC6)

KTE50026-5platesof96wells 5 plates of 96 wells
EUR 3026
Description: Quantitative sandwich ELISA for measuring Goat Troponin C, slow skeletal and cardiac muscles (TNNC6) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Goat Troponin C, slow skeletal and cardiac muscles (TNNC6)

KTE50026-96T 96T
EUR 756
Description: Quantitative sandwich ELISA for measuring Goat Troponin C, slow skeletal and cardiac muscles (TNNC6) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Troponin C, slow skeletal and cardiac muscles (TNNC1)

KTE70102-48T 48T
EUR 332
  • Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase
  • TnT, which contains the bindi
  • Show more
Description: Quantitative sandwich ELISA for measuring Mouse Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Troponin C, slow skeletal and cardiac muscles (TNNC1)

KTE70102-5platesof96wells 5 plates of 96 wells
EUR 2115
  • Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase
  • TnT, which contains the bindi
  • Show more
Description: Quantitative sandwich ELISA for measuring Mouse Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Troponin C, slow skeletal and cardiac muscles (TNNC1)

KTE70102-96T 96T
EUR 539
  • Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase
  • TnT, which contains the bindi
  • Show more
Description: Quantitative sandwich ELISA for measuring Mouse Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Custom production of antibodies in 5 Rats using customer supplied antigen (std 63 days protocol)

RAT-5 1
EUR 1138

Total Protein Extraction Kit for Muscles (50 tests)

P5A06 NULL
EUR 0

Rat Skeletal Muscle Tissue Lysate

LYSATE0010 200ug
EUR 150
Description: This cell lysate is prepared from rat skeletal muscle tissue using Boster's RIPA Lysis Buffer (AR0105) using a standard whole cell lysate protocol. The concentration was determined using the BCA assay process and then diluted using Dithiothreitol (DTT) and a reducing SDS sample loading buffer, heated for 5 minutes at 100˚C.

rno-miRNome MicroRNA Profiling Kit [Rat]

RA680B-1 20 complete profiles
EUR 1672
  • Category: MicroRNA Tools

MicroRNA Isolation Kit

KS341025 1 kit
EUR 256
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Rat Skeletal Muscle Whole tissue lysate

RAL-1467 1 mg
EUR 524

Myosin antibody (skeletal)

10R-7875 100 ug
EUR 322
Description: Mouse monoclonal Myosin antibody

Myosin antibody (skeletal)

10R-7876 100 ug
EUR 322
Description: Mouse monoclonal Myosin antibody

Cancer MicroRNA qPCR Array

RA610A-1 10 profiles
EUR 1172
  • Category: MicroRNA Tools

Rat Muscle PrimaCell1: Normal Skeletal Muscle Cells

2-82573 1 Kit Ask for price

cDNA from Rat Normal Tissue: Skeletal Muscle

C1434171 40 reactions
EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Rat Ryanodine Receptor 1, Skeletal (RYR1) Protein

20-abx654972
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Troponin-I Rat Skeletal Muscle, pure protein

TNIM50-N-25 25 ug
EUR 225

Rat Skeletal muscle Actinin Alpha ELISA kit

E02S0267-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rat Skeletal muscle Actinin Alpha in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Skeletal muscle Actinin Alpha ELISA kit

E02S0267-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rat Skeletal muscle Actinin Alpha in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Skeletal muscle Actinin Alpha ELISA kit

E02S0267-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rat Skeletal muscle Actinin Alpha in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Troponin I Skeletal Protein

abx060758-100ug 100 ug
EUR 1574
  • Shipped within 5-10 working days.

Troponin T Skeletal Protein

abx060767-05mg 0.5 mg
EUR 1713
  • Shipped within 5-10 working days.

anti-fast skeletal Myosin

YF-PA13308 50 ug
EUR 363
Description: Mouse polyclonal to fast skeletal Myosin

anti-fast skeletal Myosin

YF-PA24194 50 ul
EUR 334
Description: Mouse polyclonal to fast skeletal Myosin

SanPrep Column microRNA Miniprep Kit

SK8811 50prep
EUR 126.1
  • Product category: Molecular Biology Kits/RNA - microRNA Extraction/Multipurpose

MicroRNA scramble in CD511 - Virus

PMIRH000VA-1 1x10^6 IFUs
EUR 781
  • Category: MicroRNA Tools

MicroRNA Precursor Pooled Plasmid Library

PMIRHPLPA-1 1 aliquot plasmid DNA
EUR 50
  • Category: MicroRNA Tools

Stem Cell MicroRNA Profiling Panel

RA620A-1 10 profiles
EUR 1172
  • Category: MicroRNA Tools

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

DLR-RYR1-Ra-48T 48T
EUR 549
  • Should the Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Rat Ryanodine Receptor 1, Skeletal (RYR1) in samples from tissue homogenates, cell lysates or other biological fluids.

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

DLR-RYR1-Ra-96T 96T
EUR 718
  • Should the Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Rat Ryanodine Receptor 1, Skeletal (RYR1) in samples from tissue homogenates, cell lysates or other biological fluids.

Genomic DNA from Rat Normal Tissue: Skeletal Muscle

D1434171 100 ug
EUR 282
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

20-abx156055
  • EUR 7237.00
  • EUR 3855.00
  • EUR 895.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

Rat Ryanodine Receptor 1, Skeletal (RYR1) CLIA Kit

20-abx493893
  • EUR 8569.00
  • EUR 4560.00
  • EUR 1052.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Please enquire.

Rat Slow Skeletal Troponin I (TNNI1) CLIA Kit

20-abx494152
  • EUR 8569.00
  • EUR 4560.00
  • EUR 1052.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Please enquire.

Rat Fast Skeletal Troponin I (TNNI2) CLIA Kit

20-abx494155
  • EUR 8569.00
  • EUR 4560.00
  • EUR 1052.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Please enquire.

Rat Slow Skeletal Troponin T (TNNT1) CLIA Kit

20-abx494158
  • EUR 8569.00
  • EUR 4560.00
  • EUR 1052.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Please enquire.

Rat Actin, Alpha skeletal muscle(ACTA1) ELISA kit

E02A1218-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rat Actin, Alpha skeletal muscle(ACTA1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Actin, Alpha skeletal muscle(ACTA1) ELISA kit

E02A1218-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rat Actin, Alpha skeletal muscle(ACTA1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Actin, Alpha skeletal muscle(ACTA1) ELISA kit

E02A1218-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rat Actin, Alpha skeletal muscle(ACTA1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Actin Alpha 1, Skeletal Muscle ELISA kit

E02A0391-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rat Actin Alpha 1, Skeletal Muscle in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Actin Alpha 1, Skeletal Muscle ELISA kit

E02A0391-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rat Actin Alpha 1, Skeletal Muscle in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Actin Alpha 1, Skeletal Muscle ELISA kit

E02A0391-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rat Actin Alpha 1, Skeletal Muscle in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Ryanodine Receptor 1, Skeletal(RYR1)ELISA Kit

QY-E10032 96T
EUR 361

Rat Muscle, skeletal, receptor tyrosine kinase ELISA kit

E02M0028-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rat Muscle, skeletal, receptor tyrosine kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Muscle, skeletal, receptor tyrosine kinase ELISA kit

E02M0028-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rat Muscle, skeletal, receptor tyrosine kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Muscle, skeletal, receptor tyrosine kinase ELISA kit

E02M0028-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rat Muscle, skeletal, receptor tyrosine kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Total RNA from Rat Normal Tissue: Skeletal Muscle

R1434171-50 50 ug
EUR 152
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

SEC773Ra-10x96wellstestplate 10x96-wells test plate
EUR 5124.2
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Rat Ryanodine Receptor 1, Skeletal (RYR1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay:
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Ryanodine Receptor 1, Skeletal (RYR1) in tissue homogenates, cell lysates and other biological fluids.

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

SEC773Ra-1x48wellstestplate 1x48-wells test plate
EUR 509.64
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Rat Ryanodine Receptor 1, Skeletal (RYR1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay:
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Ryanodine Receptor 1, Skeletal (RYR1) in tissue homogenates, cell lysates and other biological fluids.

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

SEC773Ra-1x96wellstestplate 1x96-wells test plate
EUR 685.2
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Rat Ryanodine Receptor 1, Skeletal (RYR1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay:
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Ryanodine Receptor 1, Skeletal (RYR1) in tissue homogenates, cell lysates and other biological fluids.

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

SEC773Ra-5x96wellstestplate 5x96-wells test plate
EUR 2783.4
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Rat Ryanodine Receptor 1, Skeletal (RYR1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay:
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Ryanodine Receptor 1, Skeletal (RYR1) in tissue homogenates, cell lysates and other biological fluids.

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

4-SEC773Ra
  • EUR 5175.00
  • EUR 2734.00
  • EUR 686.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Ryanodine Receptor 1, Skeletal elisa. Alternative names of the recognized antigen: CCO
  • MHS
  • MHS1
  • RYDR
  • RYR
  • SKRR
  • Central Core Disease Of Muscle
  • Skeletal muscle calcium release channel
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Ryanodine Receptor 1, Skeletal (RYR1) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Rat Ryanodine Receptor 1, Skeletal ELISA Kit (RYR1)

RK03928 96 Tests
EUR 521

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

RDR-RYR1-Ra-48Tests 48 Tests
EUR 583

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

RDR-RYR1-Ra-96Tests 96 Tests
EUR 811

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

RD-RYR1-Ra-48Tests 48 Tests
EUR 557

Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit

RD-RYR1-Ra-96Tests 96 Tests
EUR 775

Rat Troponin I, slow skeletal muscle(TNNI1) ELISA kit

CSB-EL024011RA-24T 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Rat Troponin I, slow skeletal muscle (TNNI1) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat Troponin I, slow skeletal muscle(TNNI1) ELISA kit

1-CSB-EL024011RA
  • EUR 703.00
  • EUR 4843.00
  • EUR 2570.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Rat Troponin I, slow skeletal muscle(TNNI1) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat Troponin I, fast skeletal muscle(TNNI2) ELISA kit

CSB-EL024012RA-24T 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Rat Troponin I, fast skeletal muscle (TNNI2) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat Troponin I, fast skeletal muscle(TNNI2) ELISA kit

1-CSB-EL024012RA
  • EUR 804.00
  • EUR 5099.00
  • EUR 2704.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Rat Troponin I, fast skeletal muscle(TNNI2) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat Troponin T, slow skeletal muscle(TNNT1) ELISA kit

CSB-EL024015RA-24T 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Rat Troponin T, slow skeletal muscle (TNNT1) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat Troponin T, slow skeletal muscle(TNNT1) ELISA kit

1-CSB-EL024015RA
  • EUR 804.00
  • EUR 5099.00
  • EUR 2704.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Rat Troponin T, slow skeletal muscle(TNNT1) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat Troponin T, fast skeletal muscle(TNNT3) ELISA kit

CSB-EL024017RA-24T 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Rat Troponin T, fast skeletal muscle (TNNT3) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat Troponin T, fast skeletal muscle(TNNT3) ELISA kit

1-CSB-EL024017RA
  • EUR 804.00
  • EUR 5099.00
  • EUR 2704.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Rat Troponin T, fast skeletal muscle(TNNT3) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat Actin Alpha 1, Skeletal Muscle (ACTa1) ELISA Kit

DLR-ACTa1-Ra-48T 48T
EUR 528
  • Should the Rat Actin Alpha 1, Skeletal Muscle (ACTa1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Rat Actin Alpha 1, Skeletal Muscle (ACTa1) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Actin Alpha 1, Skeletal Muscle (ACTa1) ELISA Kit

DLR-ACTa1-Ra-96T 96T
EUR 690
  • Should the Rat Actin Alpha 1, Skeletal Muscle (ACTa1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Rat Actin Alpha 1, Skeletal Muscle (ACTa1) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Muscle PrimaCell1: Normal Skeletal Muscle Cells Growth Medium

9-25073 5 x 100 ml Ask for price

Rat Troponin I, Slow Skeletal Muscle (TNNI1) ELISA Kit

20-abx156169
  • EUR 7237.00
  • EUR 3855.00
  • EUR 895.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

Rat Troponin I, Fast Skeletal Muscle (TNNI2) ELISA Kit

20-abx156170
  • EUR 7237.00
  • EUR 3855.00
  • EUR 895.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

Rat Troponin T, Slow Skeletal Muscle (TNNT1) ELISA Kit

20-abx156172
  • EUR 7237.00
  • EUR 3855.00
  • EUR 895.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

Rat Troponin I Type 1, Slow Skeletal (TNNI1) Protein

20-abx069487
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.

Rat Troponin I Type 2, Fast Skeletal (TNNI2) Protein

20-abx069492
  • EUR 676.00
  • EUR 272.00
  • EUR 2068.00
  • EUR 801.00
  • EUR 481.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Rat Troponin T Type 1, Slow Skeletal (TNNT1) Protein

20-abx069498
  • EUR 718.00
  • EUR 286.00
  • EUR 2221.00
  • EUR 857.00
  • EUR 509.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.

Rat Troponin I, Fast Skeletal Muscle (TNNI2) ELISA Kit

abx256153-96tests 96 tests
EUR 746
  • Shipped within 5-12 working days.

Rat Troponin I, Slow Skeletal Muscle (TNNI1) ELISA Kit

abx256154-96tests 96 tests
EUR 746
  • Shipped within 5-12 working days.

U2AF1 mutant are preferentially killed by therapy with the compound. Altogether, our outcomes spotlight the potential of trapping early spliceosome meeting as an efficient pharmacological means to manipulate pre-mRNA splicing. By extension, we propose that stabilizing meeting intermediates could supply a helpful method for small-molecule inhibition of macromolecular machines. The software of non-viral programs for delivering genes to cells is changing into a really fascinating difficulty, particularly in the therapy of neoplasms akin to Breast Cancer (BC). Polymer-based non-viral programs are protected and possible gene carriers to be used in focused most cancers remedy. SALL4 gene encodes a transcription issue and is overexpressed in some cancers.