Enterohemorrhagic Escherichia coli serotype O157:H7 (O157) is a crucial, foodborne, human intestinal pathogen that causes extreme acute hemorrhagic diarrhea, belly cramping, and even loss of life. Small RNAs (sRNAs) are noncoding regulatory molecules that sense environmental adjustments and set off numerous virulence-related signaling pathways; nonetheless, few such sRNAs have been recognized in O157. Here, we report a novel sRNA, EsrF that senses excessive ammonium concentrations in the colon and enhances O157 pathogenicity by selling bacterial motility and adhesion to host cells.
Specifically, EsrF was discovered to instantly work together with the 5′ untranslated areas of the flagellar biosynthetic gene, flhB, mRNA and improve its abundance, thereby upregulating expression of important flagellar genes, together with flhD, flhC, fliA, and fliC, main to elevated O157 motility and virulence. Meanwhile, an toddler rabbit mannequin of O157 an infection confirmed that deletion of esrF and flhB considerably attenuates O157 pathogenicity.
Furthermore, NtrC-the response regulator of the NtrC/B two-component system-was discovered to exert direct, damaging regulation of esrF expression. Meanwhile, excessive ammonium concentrations in the colon launch the inhibitory impact of NtrC on esrF, thereby enhancing its expression and subsequently selling bacterial colonization in the host colon. Our work reveals a novel, sRNA-centered, virulence-related signaling pathway in O157 that senses excessive ammonium concentrations. These findings present novel insights for future analysis on O157 pathogenesis and focused therapy methods.
The course of by which micro organism sense environmental cues to regulate their virulence is advanced. Several research have centered on regulating the expression of the locus of enterocyte effacement pathogenicity island in the everyday intestine pathogenic bacterium, O157. However, few investigations have addressed the regulation of different virulence elements in response to intestinal indicators. In this research, we report our discovery of a novel O157 sRNA, EsrF, and show that it contributed to bacterial motility and virulence in vitro and in vivo by the regulation of bacterial flagellar synthesis.
Furthermore, we present that top ammonium concentrations in the colon induced esrF expression to promote bacterial virulence by releasing the repression of esrF by NtrC. This research highlights the significance of sRNA in regulating the motility and pathogenicity of O157. In this research, carboxyalkylated-PEI25 (25 kDa) was used to ship plasmids expressing SALL4-siRNA into MCF-7 cells. DLS and AFM had been utilized to decide the dimensions of nanoparticles. The MTT technique was used to assess cytotoxicity, and the effectivity of transfection was confirmed each qualitatively and quantitatively. Finally, the impact of silencing SALL4 was investigated on the migration of MCF7 cells utilizing the scratch check.
Polyploidy-associated paramutation in Arabidopsis is set by small RNAs, temperature, and allele construction
Paramutation is a kind of non-Mendelian inheritance in which the expression of a paramutable allele adjustments when it encounters a paramutagenic allele. This change in expression of the paramutable alleles is stably inherited even after segregation of each alleles. While the invention of paramutation and research of its underlying mechanism had been made with alleles that change plant pigmentation, paramutation-like phenomena are recognized to modulate the expression of different traits and in different eukaryotes, and many instances have most likely gone undetected.
It is probably going that epigenetic mechanisms are accountable for the phenomenon, as paramutation types epialleles, genes with similar sequences however totally different expression states. This might account for the intergenerational inheritance of the paramutated allele, offering profound proof that triggered epigenetic adjustments will be maintained over generations. Here, we use a case of paramutation that impacts a transgenic choice reporter gene in tetraploid Arabidopsis thaliana. Our information counsel that differing types of small RNA are derived from paramutable and paramutagenic epialleles.
In addition, deletion of a repeat inside the epiallele adjustments its paramutability. Further, the temperature through the progress of the epiallelic hybrids determines the diploma and timing of the allelic interplay. The information additional make it believable why paramutation in this method turns into evident solely in the segregating F2 inhabitants of tetraploid vegetation containing each epialleles. In abstract, the outcomes help a mannequin for polyploidy-associated paramutation, with similarities in addition to distinctions from different instances of paramutation.

A artificial small molecule stalls pre-mRNA splicing by selling an early-stage U2AF2-RNA advanced
Dysregulated pre-mRNA splicing is an rising Achilles heel of cancers and myelodysplasias. To develop the at present restricted portfolio of small-molecule drug leads, we screened for chemical modulators of the U2AF advanced, which nucleates spliceosome meeting and is mutated in myelodysplasias. A hit compound particularly enhances RNA binding by a U2AF2 subunit. Remarkably, the compound inhibits splicing of consultant substrates and stalls spliceosome meeting on the stage of U2AF perform. Computational docking, along with structure-guided mutagenesis, signifies that the compound bridges the tandem U2AF2 RNA recognition motifs through hydrophobic and electrostatic moieties. Cells expressing a cancer-associated
Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) Antibody |
abx238835-100ug |
Abbexa |
100 ug |
EUR 509 |
|
ELISA kit for Rat Troponin C, slow skeletal and cardiac muscles (TNNC1) |
KTE101020-48T |
Abbkine |
48T |
EUR 332 |
|
Description: Quantitative sandwich ELISA for measuring Rat Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Rat Troponin C, slow skeletal and cardiac muscles (TNNC1) |
KTE101020-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2115 |
|
Description: Quantitative sandwich ELISA for measuring Rat Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Rat Troponin C, slow skeletal and cardiac muscles (TNNC1) |
KTE101020-96T |
Abbkine |
96T |
EUR 539 |
|
Description: Quantitative sandwich ELISA for measuring Rat Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
Mouse Troponin C, slow skeletal and cardiac muscles, Tnnc1 ELISA |
ELI-36461m |
Lifescience Market |
96 Tests |
EUR 865 |
Bovine Troponin C, slow skeletal and cardiac muscles, TNNC1 ELIS |
ELI-17222b |
Lifescience Market |
96 Tests |
EUR 928 |
Porcine Troponin C, slow skeletal and cardiac muscles, TNNC1 ELI |
ELI-39993p |
Lifescience Market |
96 Tests |
EUR 928 |
Human Troponin C, slow skeletal and cardiac muscles, TNNC1 ELISA |
ELI-40072h |
Lifescience Market |
96 Tests |
EUR 824 |
Human TNNC1/ Troponin C, slow skeletal and cardiac muscles ELISA Kit |
E2558Hu |
Sunlong |
1 Kit |
EUR 605 |
Chicken Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) ELISA Kit |
abx555347-96tests |
Abbexa |
96 tests |
EUR 911 |
|
Human Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) ELISA Kit |
abx555435-96tests |
Abbexa |
96 tests |
EUR 786 |
|
Mouse Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) ELISA Kit |
abx555608-96tests |
Abbexa |
96 tests |
EUR 739 |
|
Pig Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) ELISA Kit |
abx555672-96tests |
Abbexa |
96 tests |
EUR 911 |
|
Cow Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) ELISA Kit |
abx555769-96tests |
Abbexa |
96 tests |
EUR 911 |
|
Human Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) ELISA Kit |
abx352187-96tests |
Abbexa |
96 tests |
EUR 786 |
|
Human Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) ELISA Kit |
20-abx153332 |
Abbexa |
-
EUR 7378.00
-
EUR 3933.00
-
EUR 911.00
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
ELISA kit for Human Troponin C, slow skeletal and cardiac muscles |
EK3670 |
SAB |
96 tests |
EUR 670 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Troponin C, slow skeletal and cardiac muscles in samples from serum, plasma, tissue homogenates and other biological fluids. |
ELISA kit for Mouse Troponin C, slow skeletal and cardiac muscles (TNNC1) |
KTE70102-48T |
Abbkine |
48T |
EUR 332 |
|
Description: Quantitative sandwich ELISA for measuring Mouse Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Mouse Troponin C, slow skeletal and cardiac muscles (TNNC1) |
KTE70102-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2115 |
|
Description: Quantitative sandwich ELISA for measuring Mouse Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Mouse Troponin C, slow skeletal and cardiac muscles (TNNC1) |
KTE70102-96T |
Abbkine |
96T |
EUR 539 |
|
Description: Quantitative sandwich ELISA for measuring Mouse Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Goat Troponin C, slow skeletal and cardiac muscles (TNNC6) |
KTE50026-48T |
Abbkine |
48T |
EUR 425 |
Description: Quantitative sandwich ELISA for measuring Goat Troponin C, slow skeletal and cardiac muscles (TNNC6) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Goat Troponin C, slow skeletal and cardiac muscles (TNNC6) |
KTE50026-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 3026 |
Description: Quantitative sandwich ELISA for measuring Goat Troponin C, slow skeletal and cardiac muscles (TNNC6) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Goat Troponin C, slow skeletal and cardiac muscles (TNNC6) |
KTE50026-96T |
Abbkine |
96T |
EUR 756 |
Description: Quantitative sandwich ELISA for measuring Goat Troponin C, slow skeletal and cardiac muscles (TNNC6) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Chicken Troponin C, slow skeletal and cardiac muscles (TNNC1) |
KTE30009-48T |
Abbkine |
48T |
EUR 354 |
|
Description: Quantitative sandwich ELISA for measuring Chicken Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Chicken Troponin C, slow skeletal and cardiac muscles (TNNC1) |
KTE30009-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2252 |
|
Description: Quantitative sandwich ELISA for measuring Chicken Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Chicken Troponin C, slow skeletal and cardiac muscles (TNNC1) |
KTE30009-96T |
Abbkine |
96T |
EUR 572 |
|
Description: Quantitative sandwich ELISA for measuring Chicken Troponin C, slow skeletal and cardiac muscles (TNNC1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
Custom production of antibodies in 5 Rats using customer supplied antigen (std 63 days protocol) |
RAT-5 |
Alpha Diagnostics |
1 |
EUR 1138 |
Rat Skeletal Muscle Tissue Lysate |
LYSATE0010 |
BosterBio |
200ug |
EUR 150 |
Description: This cell lysate is prepared from rat skeletal muscle tissue using Boster's RIPA Lysis Buffer (AR0105) using a standard whole cell lysate protocol. The concentration was determined using the BCA assay process and then diluted using Dithiothreitol (DTT) and a reducing SDS sample loading buffer, heated for 5 minutes at 100˚C. |
Total Protein Extraction Kit for Muscles (50 tests) |
P5A06 |
101Bio |
- |
Ask for price |
rno-miRNome MicroRNA Profiling Kit [Rat] |
RA680B-1 |
SBI |
20 complete profiles |
EUR 1672 |
|
Myosin antibody (skeletal) |
10R-7875 |
Fitzgerald |
100 ug |
EUR 322 |
Description: Mouse monoclonal Myosin antibody |
Myosin antibody (skeletal) |
10R-7876 |
Fitzgerald |
100 ug |
EUR 322 |
Description: Mouse monoclonal Myosin antibody |
Skeletal Muscle Lysate |
1407 |
ProSci |
0.1 mg |
EUR 191 |
Description: Skeletal Muscle tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT. |
Skeletal Muscle Lysate |
1467 |
ProSci |
0.1 mg |
EUR 191 |
Description: Skeletal Muscle tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT. |
Skeletal Muscle Lysate |
21-107 |
ProSci |
0.1 mg |
EUR 285.5 |
Description: Bovine skeletal muscle tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The bovine skeletal muscle tissue total protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the skeletal muscle tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The skeletal muscle tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot. |
Skeletal Muscle Lysate |
21-197 |
ProSci |
0.1 mg |
EUR 285.5 |
Description: Monkey (Cynomolgus) skeletal muscle tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The monkey (Cynomolgus) skeletal muscle tissue total protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the skeletal muscle tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The skeletal muscle tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot. |
Skeletal Muscle Lysate |
1375 |
ProSci |
0.1 mg |
EUR 191 |
Description: Skeletal Muscle tissue lysate was prepared by homogenization in lysis buffer (10 mM HEPES pH7.9, 1.5 mM MgCl2, 10 mM KCl, 1 mM ethylenediaminetetraacetic acid, 10% glycerol, 1% NP-40, and a cocktail of protease inhibitors). Tissue and cell debris was removed by centrifugation. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT. |
MicroRNA Isolation Kit |
KS341025 |
Biochain |
1 kit |
EUR 256 |
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
Rat Muscle PrimaCell1: Normal Skeletal Muscle Cells |
2-82573 |
CHI Scientific |
1 Kit |
Ask for price |
Rat Ryanodine Receptor 1, Skeletal (RYR1) Protein |
20-abx654972 |
Abbexa |
-
EUR 578.00
-
EUR 258.00
-
EUR 1720.00
-
EUR 690.00
-
EUR 425.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Troponin-I Rat Skeletal Muscle, pure protein |
TNIM50-N-25 |
Alpha Diagnostics |
25 ug |
EUR 225 |
Rat Skeletal muscle Actinin Alpha ELISA kit |
E02S0267-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A competitive ELISA for quantitative measurement of Rat Skeletal muscle Actinin Alpha in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Skeletal muscle Actinin Alpha ELISA kit |
E02S0267-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A competitive ELISA for quantitative measurement of Rat Skeletal muscle Actinin Alpha in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Skeletal muscle Actinin Alpha ELISA kit |
E02S0267-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A competitive ELISA for quantitative measurement of Rat Skeletal muscle Actinin Alpha in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
cDNA from Rat Normal Tissue: Skeletal Muscle |
C1434171 |
Biochain |
40 reactions |
EUR 376 |
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Troponin I Skeletal Protein |
abx060758-100ug |
Abbexa |
100 ug |
EUR 1574 |
|
Troponin T Skeletal Protein |
abx060767-05mg |
Abbexa |
0.5 mg |
EUR 1713 |
|
anti-fast skeletal Myosin |
YF-PA13308 |
Abfrontier |
50 ug |
EUR 363 |
Description: Mouse polyclonal to fast skeletal Myosin |
anti-fast skeletal Myosin |
YF-PA24194 |
Abfrontier |
50 ul |
EUR 334 |
Description: Mouse polyclonal to fast skeletal Myosin |
Skeletal Muscle Cytoplasmic Lysate |
XBL-10851 |
ProSci |
0.1 mg |
EUR 227.75 |
Description: human skeletal muscle tissue cytoplasmic protein lysate was prepared by isolating the cytoplasmic protein from whole tissue homogenates using a proprietary technique. The human skeletal muscle tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The cytoplasmic protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, glycerol, and a cocktail of protease inhibitors. For quality control purposes, the isolated Skeletal Muscle tissue cytoplasmic protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated Skeletal Muscle tissue cytoplasmic protein is then Western analyzed by GAPDH antibody, and the expression level is consistent with each lot. |
Skeletal Muscle Membrane Lysate |
XBL-10852 |
ProSci |
0.1 mg |
EUR 516.5 |
Description: human skeletal muscle tissue membrane protein lysate was prepared by isolating the membrane protein from whole tissue homogenates using a proprietary technique. The human skeletal muscle tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The membrane protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the isolated Skeletal Muscle tissue membrane protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated Skeletal Muscle tissue membrane protein is then Western analyzed by either GAPDH or β-actin antibody to confirm there is no signal or very weak signal. |
Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit |
SEC773Ra-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 5124.2 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Ryanodine Receptor 1, Skeletal (RYR1) in tissue homogenates, cell lysates and other biological fluids. |
Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit |
SEC773Ra-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 509.64 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Ryanodine Receptor 1, Skeletal (RYR1) in tissue homogenates, cell lysates and other biological fluids. |
Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit |
SEC773Ra-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 685.2 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Ryanodine Receptor 1, Skeletal (RYR1) in tissue homogenates, cell lysates and other biological fluids. |
Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit |
SEC773Ra-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 2783.4 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Ryanodine Receptor 1, Skeletal (RYR1) in tissue homogenates, cell lysates and other biological fluids. |
Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit |
4-SEC773Ra |
Cloud-Clone |
-
EUR 5175.00
-
EUR 2734.00
-
EUR 686.00
|
- 10 plates of 96 wells
- 5 plates of 96 wells
- 1 plate of 96 wells
|
|
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Ryanodine Receptor 1, Skeletal (RYR1) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. |
Rat Ryanodine Receptor 1, Skeletal ELISA Kit (RYR1) |
RK03928 |
Abclonal |
96 Tests |
EUR 521 |
Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit |
RD-RYR1-Ra-48Tests |
Reddot Biotech |
48 Tests |
EUR 557 |
Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit |
RD-RYR1-Ra-96Tests |
Reddot Biotech |
96 Tests |
EUR 775 |
Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit |
DLR-RYR1-Ra-48T |
DL Develop |
48T |
EUR 549 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Rat Ryanodine Receptor 1, Skeletal (RYR1) in samples from tissue homogenates, cell lysates or other biological fluids. |
Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit |
DLR-RYR1-Ra-96T |
DL Develop |
96T |
EUR 718 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Rat Ryanodine Receptor 1, Skeletal (RYR1) in samples from tissue homogenates, cell lysates or other biological fluids. |
Rat Ryanodine Receptor 1, Skeletal (RYR1) CLIA Kit |
20-abx493893 |
Abbexa |
-
EUR 8569.00
-
EUR 4560.00
-
EUR 1052.00
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Rat Slow Skeletal Troponin I (TNNI1) CLIA Kit |
20-abx494152 |
Abbexa |
-
EUR 8569.00
-
EUR 4560.00
-
EUR 1052.00
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Rat Fast Skeletal Troponin I (TNNI2) CLIA Kit |
20-abx494155 |
Abbexa |
-
EUR 8569.00
-
EUR 4560.00
-
EUR 1052.00
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Rat Slow Skeletal Troponin T (TNNT1) CLIA Kit |
20-abx494158 |
Abbexa |
-
EUR 8569.00
-
EUR 4560.00
-
EUR 1052.00
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit |
20-abx156055 |
Abbexa |
-
EUR 7237.00
-
EUR 3855.00
-
EUR 895.00
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit |
RDR-RYR1-Ra-48Tests |
Reddot Biotech |
48 Tests |
EUR 583 |
Rat Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit |
RDR-RYR1-Ra-96Tests |
Reddot Biotech |
96 Tests |
EUR 811 |
Rat Muscle, skeletal, receptor tyrosine kinase ELISA kit |
E02M0028-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A competitive ELISA for quantitative measurement of Rat Muscle, skeletal, receptor tyrosine kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Muscle, skeletal, receptor tyrosine kinase ELISA kit |
E02M0028-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A competitive ELISA for quantitative measurement of Rat Muscle, skeletal, receptor tyrosine kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Muscle, skeletal, receptor tyrosine kinase ELISA kit |
E02M0028-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A competitive ELISA for quantitative measurement of Rat Muscle, skeletal, receptor tyrosine kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Actin Alpha 1, Skeletal Muscle ELISA kit |
E02A0391-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A competitive ELISA for quantitative measurement of Rat Actin Alpha 1, Skeletal Muscle in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Actin Alpha 1, Skeletal Muscle ELISA kit |
E02A0391-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A competitive ELISA for quantitative measurement of Rat Actin Alpha 1, Skeletal Muscle in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Actin Alpha 1, Skeletal Muscle ELISA kit |
E02A0391-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A competitive ELISA for quantitative measurement of Rat Actin Alpha 1, Skeletal Muscle in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Actin, Alpha skeletal muscle(ACTA1) ELISA kit |
E02A1218-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A competitive ELISA for quantitative measurement of Rat Actin, Alpha skeletal muscle(ACTA1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Actin, Alpha skeletal muscle(ACTA1) ELISA kit |
E02A1218-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A competitive ELISA for quantitative measurement of Rat Actin, Alpha skeletal muscle(ACTA1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Actin, Alpha skeletal muscle(ACTA1) ELISA kit |
E02A1218-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A competitive ELISA for quantitative measurement of Rat Actin, Alpha skeletal muscle(ACTA1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Genomic DNA from Rat Normal Tissue: Skeletal Muscle |
D1434171 |
Biochain |
100 ug |
EUR 282 |
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Rat Normal Tissue: Skeletal Muscle |
R1434171-50 |
Biochain |
50 ug |
EUR 152 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Cancer MicroRNA qPCR Array |
RA610A-1 |
SBI |
10 profiles |
EUR 1172 |
|
Mouse Skeletal Muscle Tissue Lysate |
LYSATE0021 |
BosterBio |
200ug |
EUR 150 |
Description: This cell lysate is prepared from mouse skeletal muscle tissue using Boster's RIPA Lysis Buffer (AR0105) using a standard whole cell lysate protocol. The concentration was determined using the BCA assay process and then diluted using Dithiothreitol (DTT) and a reducing SDS sample loading buffer, heated for 5 minutes at 100˚C. |
? skeletal muscle actin Monoclonal Antibody |
EM1149-100ul |
ELK Biotech |
100ul |
EUR 279 |
Description: A Mouse Monoclonal antibody against ? skeletal muscle actin from Human/ Rat/ Mouse. This antibody is tested and validated for WB, ELISA, IHC |
? skeletal muscle actin Monoclonal Antibody |
EM1149-50ul |
ELK Biotech |
50ul |
EUR 207 |
Description: A Mouse Monoclonal antibody against ? skeletal muscle actin from Human/ Rat/ Mouse. This antibody is tested and validated for WB, ELISA, IHC |
?-Skeletal Muscle Actin Polyclonal Antibody |
EA047-100ul |
ELK Biotech |
100ul |
EUR 279 |
Description: A Rabbit Polyclonal antibody against ?-Skeletal Muscle Actin from Human/ Rat/ Mouse. This antibody is tested and validated for WB, ELISA, IHC |
?-Skeletal Muscle Actin Polyclonal Antibody |
EA047-50ul |
ELK Biotech |
50ul |
EUR 207 |
Description: A Rabbit Polyclonal antibody against ?-Skeletal Muscle Actin from Human/ Rat/ Mouse. This antibody is tested and validated for WB, ELISA, IHC |
?-Skeletal Muscle Actin Polyclonal Antibody |
ES1176-100ul |
ELK Biotech |
100ul |
EUR 279 |
Description: A Rabbit Polyclonal antibody against ?-Skeletal Muscle Actin from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA |
?-Skeletal Muscle Actin Polyclonal Antibody |
ES1176-50ul |
ELK Biotech |
50ul |
EUR 207 |
Description: A Rabbit Polyclonal antibody against ?-Skeletal Muscle Actin from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA |
alpha Actin (skeletal muscle) Antibody |
35512-100ul |
SAB |
100ul |
EUR 390 |
Rabbit Skeletal Muscle Troponin-C |
7-06205 |
CHI Scientific |
1mg |
Ask for price |
Rabbit Skeletal Muscle Troponin-C |
7-06206 |
CHI Scientific |
5mg |
Ask for price |
Rabbit Skeletal Muscle Troponin-C |
7-06207 |
CHI Scientific |
10mg |
Ask for price |
Troponin I Skeletal Muscle Antibody |
abx020870-1mg |
Abbexa |
1 mg |
EUR 815 |
|
Troponin I Skeletal Muscle Antibody |
abx020871-1mg |
Abbexa |
1 mg |
EUR 815 |
|
Anti-fast skeletal Myosin (2D9) |
YF-MA10603 |
Abfrontier |
100 ug |
EUR 363 |
Description: Mouse monoclonal to fast skeletal Myosin |
Anti-fast skeletal Myosin (3H3) |
YF-MA18264 |
Abfrontier |
100 ug |
EUR 363 |
Description: Mouse monoclonal to fast skeletal Myosin |
Anti-fast skeletal Myosin (1B22) |
YF-MA19700 |
Abfrontier |
100 ug |
EUR 363 |
Description: Mouse monoclonal to fast skeletal Myosin |
U2AF1 mutant are preferentially killed by therapy with the compound. Altogether, our outcomes spotlight the potential of trapping early spliceosome meeting as an efficient pharmacological means to manipulate pre-mRNA splicing. By extension, we propose that stabilizing meeting intermediates could supply a helpful method for small-molecule inhibition of macromolecular machines. The software of non-viral programs for delivering genes to cells is changing into a really fascinating difficulty, particularly in the therapy of neoplasms akin to Breast Cancer (BC). Polymer-based non-viral programs are protected and possible gene carriers to be used in focused most cancers remedy. SALL4 gene encodes a transcription issue and is overexpressed in some cancers.