The intention of the current examine was to make clear the impact of lengthy non-coding RNA (lncRNA) small nucleolar RNA host gene 1 (SNHG1) on the proliferation, migration and invasion of osteosarcoma (OS) cells and to discover the potential underlying mechanisms. The expression ranges of SNHG1, microRNA (miR)-424-5p and fibroblast progress issue 2 (FGF2) in OS tissues and cells have been detected utilizing reverse transcription-quantitative polymerase chain response. OS cell proliferation, migration and invasion have been analysed by MTT, wound therapeutic and Transwell invasion assays, respectively.
The concentrating on relationships between SNHG1 and miR-424-5p, in addition to between miR-424-5p and FGF2, have been confirmed utilizing RNA-binding protein immunoprecipitation and/or dual-luciferase reporter gene assays. The outcomes demonstrated that the expression ranges of SNHG1 and FGF2 have been upregulated, whereas the expression of miR-424-5p was downregulated in OS tissues and cells. The silencing of SNHG1 considerably inhibited the proliferation, migration and invasion of OS cells. Additionally, FGF2 was proven to be a goal of miR-424-5p, which in flip, was a goal of SNHG1. miR-424-5p silencing and FGF2 overexpression each reversed the suppressive results of SNHG1 knockdown on the proliferation, migration and invasion of OS cells.
Viral interfering RNA (viRNA) has been recognized from a number of viral genomes by way of straight deep RNA sequencing of the virus-infected cells, together with zika virus (ZIKV). Once produced by endoribonuclease Dicer, viRNAs are loaded onto the Argonaute (AGO) household proteins of the RNA-induced silencing complexes (RISCs) to pair with their RNA targets and provoke the cleavage of goal genes. However, the identities of useful ZIKV viRNAs and their viral RNA targets stay largely unknown. Thus, the silencing of SNHG1 could inhibit the proliferation, migration and invasion of OS cells by regulating the miR-424-5p/FGF2 axis.
Our latest examine has proven that ZIKV capsid protein interacted with Dicer and antagonized its endoribonuclease exercise, which requires its histidine residue at the 41st amino acid. Accordingly, the engineered ZIKV-H41R loss-of-function (LOF) mutant virus not suppresses Dicer enzymatic exercise nor inhibits miRNA biogenesis in NSCs. By combining AGO-associated RNA sequencing, deep sequencing evaluation in ZIKV-infected human neural stem cells (NSCs), and miRanda goal scanning, we outlined 29 ZIKV derived viRNA profiles in NSCs, and established a posh interplay community between the viRNAs and their viral targets. ‘
More importantly, we discovered that viRNA manufacturing from the ZIKV mRNA relies on Dicer operate and is a limiting issue for ZIKV virulence in NSCs. As a consequence, a lot greater ranges of viRNAs generated from the ZIKV-H41R virus-infected NSCs. Therefore, our mapping of viRNAs to their RNA targets paves a option to additional examine how viRNAs play the function in anti-viral mechanisms, and maybe different unknown organic features.
Stress resets ancestral heritable small RNA responses
Transgenerational inheritance of small RNAs challenges primary ideas of heredity. In C. elegans nematodes, small RNAs are transmitted throughout generations to ascertain a transgenerational reminiscence hint of ancestral environments and distinguish self-genes from non-self-elements. Carryover of aberrant heritable small RNA responses was proven to be maladaptive and to result in sterility. Here we present that numerous varieties of stress (hunger, excessive temperatures, and excessive osmolarity) induce resetting of ancestral small RNA responses and a genome-wide discount in heritable small RNA ranges.
We discovered that mutants which can be faulty in numerous stress pathways exhibit irregular RNAi inheritance dynamics even in the absence of stress. Moreover, we found that resetting of ancestral RNAi responses is particularly orchestrated by elements that operate in the p38 MAPK pathway and the transcription issue SKN-1/Nrf2. Stress-dependent termination of small RNA inheritance may defend from run-on of environment-irrelevant heritable gene regulation. In conclusion, AGT siRNA exerts renoprotection in the 5/sixth Nx mannequin in a blood pressure-independent method. This depends on the suppression of renal Ang II formation from liver-derived AGT. Consequently, AGT siRNA could show useful in human power kidney illness.
Renoprotective Effects of Small Interfering RNA Targeting Liver Angiotensinogen in Experimental Chronic Kidney Disease
Small interfering RNA (siRNA) concentrating on liver angiotensinogen (AGT) lowers blood stress, however its effectiveness in hypertensive power kidney illness is unknown. Considering that the kidney could generate its personal AGT, we assessed the effectiveness of liver-targeted AGT siRNA in the 5/sixth Nx (5/sixth nephrectomy) rat-a hypertensive power kidney illness mannequin. Five weeks after 5/sixth Nx (baseline), rats have been subjected to automobile, AGT siRNA, AGT siRNA+losartan, losartan, or losartan+captopril. Baseline imply arterial stress was 160±6 mm Hg. Over the course of four weeks, imply arterial stress elevated additional by ≈15 mm Hg throughout automobile remedy. This rise was prevented by AGT siRNA.
 Total RNA from Liver Cirrhosis: Kidney |
|
R1236142Lcs-50 |
Biochain |
50 ug |
EUR 351 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Liver Cirrhosis: Lung |
|
R1236152Lcs-50 |
Biochain |
50 ug |
EUR 351 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Liver Cirrhosis: Diaphragm |
|
R1236169Lcs-50 |
Biochain |
50 ug |
EUR 351 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Liver Cirrhosis: Pancreas |
|
R1236188Lcs-50 |
Biochain |
50 ug |
EUR 351 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Liver Cirrhosis: Rectum |
|
R1236206Lcs-50 |
Biochain |
50 ug |
EUR 351 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Liver Cirrhosis: Spleen |
|
R1236246Lcs-50 |
Biochain |
50 ug |
EUR 351 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Human Tumor Tissue: Liver |
|
R1235149-50 |
Biochain |
50 ug |
EUR 351 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Liver Cirrhosis: Small Intestine |
|
R1236226Lcs-50 |
Biochain |
50 ug |
EUR 351 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Mouse Normal Tissue: Liver |
|
R1334149-50 |
Biochain |
50 ug |
EUR 152 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Human Adult Normal Tissue: Liver |
|
R1234149-50 |
Biochain |
50 ug |
EUR 178 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Normal Tissue: Liver) Total RNA from Monkey (Rhesus) Normal Tissue: Liver |
|
R1534149-50 |
Biochain |
50 ug |
EUR 194 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Normal Tissue: Liver) Total RNA from Monkey (Cynomolgus) Normal Tissue: Liver |
|
R1534149-Cy |
Biochain |
50 ug |
EUR 194 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 FFPE Total RNA - Human Adult Normal Tissue: Liver |
|
R2234149 |
Biochain |
1 ug |
EUR 628 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
) Plant Total RNA Mini Kit (100prep) |
|
FAPRK-001-1 |
Favorgen |
100 preps |
EUR 216 |
) Plant Total RNA Maxi Kit (24prep) |
|
FAPRK-002-1 |
Favorgen |
24 preps |
EUR 317 |
) Tissue Total RNA Mini Kit (100prep) |
|
FATRK-001-1 |
Favorgen |
100 preps |
EUR 216 |
) Tissue Total RNA Maxi Kit (24prep) |
|
FATRK-003-1 |
Favorgen |
24 preps |
EUR 317 |
 Total Protein from Liver Cirrhosis: Liver |
|
P1236149Lcs |
Biochain |
1 mg |
EUR 461 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 ELISA Kit) Human Total PSA (t-PSA) ELISA Kit |
|
PRB-5049-TOTAL |
Cell Biolabs |
96 assays |
EUR 572 |
 Total RNA from Human Normal Lymphocyte Cell Line |
|
R1254148-1 |
Biochain |
100 ug |
EUR 228 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Human Adult Normal Tissue: Liver: Left Lobe |
|
R1234150-50 |
Biochain |
50 ug |
EUR 178 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Human Adult Normal Tissue: Liver: Right Lobe |
|
R1234151-50 |
Biochain |
50 ug |
EUR 178 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Green RNA Lysis Kit 50 |
|
GREENE1-RNA |
Next Advance |
50pack |
EUR 180 |
|
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free. |
 Green RNA Lysis Kit 250 |
|
GREENE5-RNA |
Next Advance |
250pack |
EUR 571 |
|
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free. |
 Pink RNA Lysis Kit 50 |
|
PINKE1-RNA |
Next Advance |
50pack |
EUR 178 |
|
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
 Pink RNA Lysis Kit 250 |
|
PINKE5-RNA |
Next Advance |
250pack |
EUR 561 |
|
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
 Navy RNA Lysis Kit 50 |
|
NAVYE1-RNA |
Next Advance |
50pack |
EUR 198 |
|
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free. |
 Navy RNA Lysis Kit 250 |
|
NAVYE5-RNA |
Next Advance |
250pack |
EUR 651 |
|
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free. |
 Red RNA Lysis Kit 50 |
|
REDE1-RNA |
Next Advance |
50pack |
EUR 192 |
|
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
 Red RNA Lysis Kit 250 |
|
REDE5-RNA |
Next Advance |
250pack |
EUR 622 |
|
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
 YELLOW RNA Lysis Kit 50 |
|
YELLOWE1-RNA |
Next Advance |
50pack |
EUR 192 |
|
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
 YELLOW RNA Lysis Kit 250 |
|
YELLOWE5-RNA |
Next Advance |
250pack |
EUR 624 |
|
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
 RNA isolater Total RNA Extraction Reagent |
|
R401-01 |
Vazyme |
100 ml |
EUR 133 |
 Total RNA Extraction Kit |
|
K2014005 |
Biochain |
1 kit |
EUR 344 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total RNA Isolation Kit |
|
P-9100 |
EpiGentek |
50 samples |
EUR 347.25 |
|
Description: The best epigenetics products |
) Blood/Cultured Cell Total RNA Mini Kit (100prep) |
|
FABRK-001-1 |
Favorgen |
100 preps |
EUR 216 |
) Blood/Cultured Cell Total RNA Maxi Kit (24prep) |
|
FABRK-003-1 |
Favorgen |
24 preps |
EUR 317 |
 Total RNA from Human Adult Normal Tissue: Liver, Ambient temperature shipping |
|
ATR1234149-50 |
Biochain |
50 ug |
EUR 190 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Human Adult Normal Tissue 5 Donor Pool: Liver |
|
R1234149-P |
Biochain |
50 ug |
EUR 328 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total Protein from Lupus: Liver |
|
P1236149Lup |
Biochain |
1 mg |
EUR 461 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 5E GREEN RNA Lysis Kit 100 |
|
GREEN5E100-RNA |
Next Advance |
100pack |
EUR 386 |
|
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 1000, 5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free. |
 5E GREEN RNA Lysis Kit 20 |
|
GREEN5E20-RNA |
Next Advance |
20pack |
EUR 138 |
|
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free. |
 Green RINO RNA Lysis Kit 50 |
|
GREENR1-RNA |
Next Advance |
50pack |
EUR 184 |
|
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with beads. RNase free. |
 Green RINO RNA Lysis Kit 250 |
|
GREENR5-RNA |
Next Advance |
250pack |
EUR 587 |
|
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with beads. RNase free. |
 5E PINK RNA Lysis Kit 100 |
|
PINK5E100-RNA |
Next Advance |
100pack |
EUR 380 |
|
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
 5E PINK RNA Lysis Kit 20 |
|
PINK5E20-RNA |
Next Advance |
20pack |
EUR 136 |
|
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
 Pink RINO RNA Lysis Kit 50 |
|
PINKR1-RNA |
Next Advance |
50pack |
EUR 181 |
|
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free. |
 Pink RINO RNA Lysis Kit 250 |
|
PINKR5-RNA |
Next Advance |
250pack |
EUR 576 |
|
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free. |
 Navy RINO RNA Lysis Kit 250 |
|
NAVYR5-RNA |
Next Advance |
250pack |
EUR 666 |
|
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stainless steel beads. RNase free. |
 5E Navy RNA Lysis Kit 100 |
|
NAVY5E100-RNA |
Next Advance |
100pack |
EUR 453 |
|
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free. |
 5E Navy RNA Lysis Kit 20 |
|
NAVY5E20-RNA |
Next Advance |
20pack |
EUR 153 |
|
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free. |
 Navy RINO RNA Lysis Kit 50 |
|
NAVYR1-RNA |
Next Advance |
50pack |
EUR 202 |
|
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stainless steel beads. RNase free. |
 5E RED RNA Lysis Kit 100 |
|
RED5E100-RNA |
Next Advance |
100pack |
EUR 429 |
|
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
 5E RED RNA Lysis Kit 20 |
|
RED5E20-RNA |
Next Advance |
20pack |
EUR 148 |
|
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
 Red RINO RNA Lysis Kit 50 |
|
REDR1-RNA |
Next Advance |
50pack |
EUR 195 |
|
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free. |
 Red RINO RNA Lysis Kit 250 |
|
REDR5-RNA |
Next Advance |
250pack |
EUR 638 |
|
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free. |
 YELLOW RINO RNA Lysis Kit 50 |
|
YELLOWR1-RNA |
Next Advance |
50pack |
EUR 199 |
|
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free. |
 YELLOW RINO RNA Lysis Kit 250 |
|
YELLOWR5-RNA |
Next Advance |
250pack |
EUR 656 |
|
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free. |
Human Total PSA (t-PSA) ELISA Kit |
|
PRB-5049-TOTAL-5 |
Cell Biolabs |
5 x 96 assays |
EUR 2283 |
 Liver Cancer Exosome RNA |
|
P241-LV |
101Bio |
- |
Ask for price |
 Bovine LIVER 1 EA* |
|
57123-1 |
Pel-Freez |
1 Each |
EUR 180.28 |
, for Woody Plant) Plant Total RNA Mini Kit (100prep), for Woody Plant |
|
FAPRK-003-1 |
Favorgen |
100 preps |
EUR 223 |
 FFPE and Frozen Matching Pair Total RNA: Human Adult Normal Tissue: Liver |
|
R8234149-FP |
Biochain |
2x1 ug |
EUR 1361 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Matching Pair - Total RNA from Human Primary and Metastatic Tumor Tissue: Liver |
|
R8235149-PM-10 |
Biochain |
2x10 ug |
EUR 650 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Matching Pair - Total RNA from Human Primary Tumor and Normal Tissue: Liver |
|
R8235149-PP-10 |
Biochain |
2x10 ug |
EUR 439 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
) 96-well Total RNA Kit (1 plates) |
|
FATRE-96001 |
Favorgen |
1 prep |
EUR 194 |
 Total RNA from Rat Normal Tissue: Adipose |
|
R1434003-50 |
Biochain |
50 ug |
EUR 214 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Rat Normal Tissue: Bladder |
|
R1434010-50 |
Biochain |
50 ug |
EUR 303 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Rat Normal Tissue: Brain |
|
R1434035-50 |
Biochain |
50 ug |
EUR 152 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Rat Normal Tissue: Colon |
|
R1434090-50 |
Biochain |
50 ug |
EUR 152 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Rat Normal Tissue: Heart |
|
R1434122-50 |
Biochain |
50 ug |
EUR 152 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Rat Normal Tissue: Kidney |
|
R1434142-50 |
Biochain |
50 ug |
EUR 152 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Rat Normal Tissue: Lung |
|
R1434152-50 |
Biochain |
50 ug |
EUR 152 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Rat Normal Tissue: Ovary |
|
R1434183-50 |
Biochain |
50 ug |
EUR 296 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Rat Normal Tissue: Pancreas |
|
R1434188-50 |
Biochain |
50 ug |
EUR 296 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Rat Normal Tissue: Placenta |
|
R1434200-50 |
Biochain |
50 ug |
EUR 214 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Rat Normal Tissue: Rectum |
|
R1434206-50 |
Biochain |
50 ug |
EUR 214 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Rat Normal Tissue: Spleen |
|
R1434246-50 |
Biochain |
50 ug |
EUR 152 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Rat Normal Tissue: Stomach |
|
R1434248-50 |
Biochain |
50 ug |
EUR 214 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Rat Normal Tissue: Testis |
|
R1434260-50 |
Biochain |
50 ug |
EUR 152 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Rat Normal Tissue: Thymus |
|
R1434264-50 |
Biochain |
50 ug |
EUR 214 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Human Normal Lymphocyte Cell Line, Ambient temperature shipping |
|
ATR1254148-1 |
Biochain |
100 ug |
EUR 221 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 AnaPrep Total RNA Extraction Kit |
|
Z1322015 |
Biochain |
1 kit (48 extractions) Including all required plastic disposables |
EUR 308 |
|
Description: This kit is developped for our fully automated magnetic bead-based nucleic acid extraction platform which uses preprogrammed protocols and can process up to 12 samples simultaneously. With the AnaPrep 12 Extractor you will have the option to choose and work with a wide range of sample and reagent volumes. This sturdy, realiable and user-friendly machine will save you both time and expenses while ensuring consistently high quality performance and nucleic acids for your downstream applications. |
 Total RNA from Lupus: Colon |
|
R1236090Lup-50 |
Biochain |
50 ug |
EUR 351 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from hypertension: Heart |
|
R1236122Hd-2 |
Biochain |
50 ug |
EUR 351 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Lupus: Kidney |
|
R1236142Lup-50 |
Biochain |
50 ug |
EUR 351 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Lupus: Lung |
|
R1236152Lup-50 |
Biochain |
50 ug |
EUR 351 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Lupus: Pancreas |
|
R1236188Lup-50 |
Biochain |
50 ug |
EUR 351 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Lupus: Spleen |
|
R1236246Lup-50 |
Biochain |
50 ug |
EUR 351 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Lupus: Stomach |
|
R1236248Lup-50 |
Biochain |
50 ug |
EUR 351 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Lupus: Uterus |
|
R1236274Lup-50 |
Biochain |
50 ug |
EUR 351 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA Isolation Kit II |
|
FATRS--001 |
Favorgen |
100 preps |
EUR 308 |
Total RNA Isolation Kit II |
|
FATRS--050 |
Favorgen |
50 preps |
EUR 216 |
) Total RNA Isolation Kit (Tissue) |
|
P-9102 |
EpiGentek |
50 samples |
EUR 347.25 |
|
Description: reagents widely cited |
) Total RNA Isolation Kit (Plant) |
|
P-9104 |
EpiGentek |
50 samples |
EUR 347.25 |
|
Description: kits suitable for this type of research |
 Total RNA ExtractionMini KitAnimal Tissues |
|
FYG301-50P |
Yeastern Biotech |
50 Preps |
Ask for price |
Total RNA ExtractionMini KitAnimal Tissues |
|
FYG302-100P |
Yeastern Biotech |
100 Preps |
Ask for price |
Total RNA ExtractionMini KitAnimal Tissues |
|
FYG302-300P |
Yeastern Biotech |
300 Preps |
Ask for price |
 Total RNA ExtractionMini KitPlant Tissues |
|
FYG303-100P |
Yeastern Biotech |
100 Preps |
Ask for price |
Total RNA ExtractionMini KitPlant Tissues |
|
FYG303-300P |
Yeastern Biotech |
300 Preps |
Ask for price |
Total RNA ExtractionMini KitPlant Tissues |
|
FYG303-50P |
Yeastern Biotech |
50 Preps |
Ask for price |
 Immortalized Human Total Liver Cell Population |
|
T0581 |
ABM |
1x106 cells / 1.0 ml |
Ask for price |
 Total Protein from Liver Cirrhosis: Adrenal |
|
P1236004Lcs |
Biochain |
1 mg |
EUR 461 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total Protein from Liver Cirrhosis: Appendix |
|
P1236006Lcs |
Biochain |
1 mg |
EUR 461 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total Protein from Liver Cirrhosis: Brain |
|
P1236035Lcs |
Biochain |
1 mg |
EUR 461 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total Protein from Liver Cirrhosis: Colon |
|
P1236090Lcs |
Biochain |
1 mg |
EUR 461 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total Protein from Liver Cirrhosis: Esophagus |
|
P1236106Lcs |
Biochain |
1 mg |
EUR 461 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total Protein from Liver Cirrhosis: Gallbladder |
|
P1236118Lcs |
Biochain |
1 mg |
EUR 461 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total Protein from Liver Cirrhosis: Heart |
|
P1236122Lcs |
Biochain |
1 mg |
EUR 461 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total Protein from Liver Cirrhosis: Kidney |
|
P1236142Lcs |
Biochain |
1 mg |
EUR 461 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total Protein from Liver Cirrhosis: Lung |
|
P1236152Lcs |
Biochain |
1 mg |
EUR 461 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total Protein from Liver Cirrhosis: Diaphragm |
|
P1236169Lcs |
Biochain |
1 mg |
EUR 461 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total Protein from Liver Cirrhosis: Pancreas |
|
P1236188Lcs |
Biochain |
1 mg |
EUR 461 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total Protein from Liver Cirrhosis: Prostate |
|
P1236201Lcs |
Biochain |
1 mg |
EUR 461 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total Protein from Liver Cirrhosis: Rectum |
|
P1236206Lcs |
Biochain |
1 mg |
EUR 461 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total Protein from Liver Cirrhosis: Skin |
|
P1236218Lcs |
Biochain |
1 mg |
EUR 461 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total Protein from Liver Cirrhosis: Spleen |
|
P1236246Lcs |
Biochain |
1 mg |
EUR 461 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total Protein from Liver Cirrhosis: Testis |
|
P1236260Lcs |
Biochain |
1 mg |
EUR 461 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total Protein from Liver Cirrhosis: Thyroid |
|
P1236265Lcs |
Biochain |
1 mg |
EUR 461 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total RNA from Rat Normal Tissue: Brain, cerebellum |
|
R1434039-50 |
Biochain |
50 ug |
EUR 152 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Rat Normal Tissue: Skeletal Muscle |
|
R1434171-50 |
Biochain |
50 ug |
EUR 152 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Rat Normal Tissue: Small Intestine |
|
R1434226-50 |
Biochain |
50 ug |
EUR 214 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Anti-Liver Carboxylesterase 1/CES1 Antibody |
|
A01741-1 |
BosterBio |
100ug/vial |
EUR 334 |
 Total Protein from Human Tumor Tissue: Liver |
|
P1235149 |
Biochain |
1 mg |
EUR 320 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total Protein from Human Diabetic Tissue: Liver |
|
P1236149Dia |
Biochain |
1 mg |
EUR 461 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total Protein from Lupus: Liver: Left Lobe |
|
P1236150Lup |
Biochain |
1 mg |
EUR 461 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total Protein from Lupus: Liver: Right Lobe |
|
P1236151Lup |
Biochain |
1 mg |
EUR 461 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total Protein from Liver Cirrhosis: Lymph Node |
|
P1236161Lcs |
Biochain |
1 mg |
EUR 461 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total Protein from Liver Cirrhosis: Small Intestine |
|
P1236226Lcs |
Biochain |
1 mg |
EUR 461 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total Protein from Liver Cirrhosis: Spinal Cord |
|
P1236234Lcs |
Biochain |
1 mg |
EUR 461 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total Protein from Mouse Normal Tissue: Liver |
|
P1334149 |
Biochain |
1 mg |
EUR 214 |
|
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
 Total RNA from Alzheimer's Disease: Brain |
|
R1236035Alz-50 |
Biochain |
50 ug |
EUR 351 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Alzheimer's Disease: Pons |
|
R1236071Alz-10 |
Biochain |
10 ug |
EUR 351 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
 Total RNA from Diabetic Disease: Colon |
|
R1236090Dia-50 |
Biochain |
50 ug |
EUR 351 |
|
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Losartan lowered imply arterial stress by 37±6 mm Hg and elevated plasma Ang (angiotensin) II. Both AGT siRNA and captopril suppressed these results of losartan, suggesting that its blood pressure-lowering impact relied on stimulation of vasodilator Ang II kind 2 receptors by excessive Ang II ranges. Proteinuria and cardiac hypertrophy elevated with automobile, and these will increase have been comparably abrogated by all remedies. No intervention improved glomerular filtration charge, whereas siRNA and losartan equally diminished glomerulosclerosis. AGT siRNA±losartan lowered plasma AGT by >95%, and this was accompanied by virtually full elimination of Ang II in kidney and coronary heart, with out lowering renal AGT mRNA. Multiple linear regression confirmed each imply arterial stress and renal Ang II as impartial determinants of proteinuria.
