Transfer RNA (tRNA)-derived small RNAs (tsRNAs) have been discovered to play vital roles in the incidence and improvement of cancers. However, the tsRNA profile in gastric cancer is unknown. In this examine, we aimed to determine the worldwide tsRNA profile in plasma from gastric cancer sufferers and elucidate the function of tRF-33-P4R8YP9LON4VDP in gastric cancer. Differentially expressed tsRNAs in the plasma of gastric cancer sufferers and wholesome controls had been investigated utilizing RNA sequencing.
The expression ranges of tRF-33-P4R8YP9LON4VDP in the plasma of gastric cancer sufferers, wholesome controls and gastric cancer cell strains had been first detected by quantitative reverse transcription-polymerase chain response. The results of tRF-33-P4R8YP9LON4VDP overexpression or downregulation in gastric cancer cells on proliferation, migration, apoptosis, and cell cycle had been analyzed utilizing the Cell Counting Kit-8, scratch assay, Transwell assay, and circulation cytometry, respectively. There had been 21 upregulated and 46 downregulated tsRNAs discovered in plasma from gastric cancer sufferers.
Glioblastoma multiforme (GBM) is one of the worst mind tumors arising from glial cells, inflicting many deaths yearly. Surgery, chemotherapy, radiotherapy and immunotherapy are used for GBM therapy. However, GBM continues to be an incurable illness, and new approaches are required for its profitable therapy. Because mutations and amplifications occurring in a number of genes are answerable for the development and aggressive habits of GBM cells, genetic approaches are of nice significance in its therapy. Small interfering RNA (siRNA) is a new rising software to silence the genes answerable for illness development, significantly cancer. SiRNA can be utilized for GBM therapy by down-regulating genes such as VEGF, STAT3, ELTD1 or EGFR.
Furthermore, the use of siRNA can promote the chemosensitivity of GBM cells. However, the effectivity of siRNA in GBM is restricted by its degradation by enzymes, and its off-targeting results. SiRNA-loaded carriers, particularly nanovehicles which are ligand-functionalized by CXCR4 or angiopep-2, can be utilized for the safety and focused supply of siRNA. Nanostructures can present a platform for co-delivery of siRNA plus anti-tumor medicine as one other profit. The ready nanovehicles needs to be steady and biocompatible in order to be examined in human research.
Long non-coding RNA NEAT1 regulates ferroptosis sensitivity in non-small-cell lung cancer
Ferroptosis is brought on by iron-dependent lipid peroxide accumulation, the sensitivity of which is perhaps regulated by acyl-CoA synthetase lengthy chain member of the family 4 (ACSL4). Non-small-cell lung cancer (NSCLC) can resist oxidative stress and scale back the sensitivity of tumor cells to ferroptosis by altering the expression of some proteins. Mechanisms involving ferroptosis sensitivity in NSCLC aren’t absolutely understood. NEAT1 regulates ferroptosis and ferroptosis sensitivity, with the latter relying on ACSL4, suggesting that focusing on NEAT1 or ACSL4 could also be a viable therapeutic strategy to the therapy of NSCLC.
A dual-luciferase reporter assay was used to verify a focusing on relationship between lengthy non-coding (lnc)RNA NEAT1 and ACSL4. Overexpression and silencing assays of NEAT1 operate had been used to find out its roles in cell loss of life (by TUNEL staining) and lipid peroxidation (by malondialdehyde ranges). Expression of ferroptosis-related proteins (SLCA11, GPX4, and TFR4) was evaluated by western blot in NSCLC cells handled or not with the ferroptosis inducer erastin. In this mini-review, the small molecules divided into 4 sorts are expounded which centered primarily on their structural options and organic actions.
Extensive proof signifies that RNA G-quadruplexes have related to some vital mobile occasions. Investigation of RNA G-quadruplexes is thus very important to revealing their biofunctions. Several small molecules have been developed to focus on RNA G-quadruplexes to this point. Some of the small molecules confirmed considerably light-up fluorescence alerts upon binding to RNA G-quadruplexes, whereas some of them regulated the biofunctions of RNA G-quadruplexes. Moreover, we raised the present challenges and promising prospects. This mini-review may contribute to exploiting extra subtle small molecules focusing on RNA G-quadruplexes with excessive specificity based mostly on the reported chemical structural options.
Plant ARGONAUTE Protein Immunopurification for Pathogen Cross Kingdom Small RNA Analysis
Over the final decade, it has been seen that microbial pathogens and pests ship small RNA (sRNA) effectors into their host crops to govern plant physiology and immunity for an infection, identified as cross kingdom RNA interference. In this course of, fungal and oomycete parasite sRNAs hijack the plant ARGONAUTE (AGO)/RNA-induced silencing advanced to post-transcriptionally silence host goal genes. We hereby describe the methodological particulars of how we recovered cross kingdom sRNA effectors of the oomycete pathogen Hyaloperonospora arabidopsidis throughout an infection of its host plant Arabidopsis thaliana.
This Bio-protocol accommodates two elements: first, a detailed description on the process of plant AGO/sRNA co-immunopurification and sRNA restoration for Illumina excessive throughput sequencing evaluation. Second, we clarify how you can carry out bioinformatics evaluation of sRNA sequence reads utilizing a Galaxy server. In precept, this protocol is appropriate to analyze AGO-bound sRNAs from various host crops and plant-interacting (micro)organisms. RNA-based therapeutics have emerged as one of essentially the most highly effective therapeutic choices used for the modulation of gene/protein expression and gene enhancing with the potential to deal with neurodegenerative ailments.
Brain Dissociation System 5 (Cerebral cortex), Mouse and Rat |
4-20225 |
CHI Scientific |
ea |
Ask for price |
Human Total PSA (t-PSA) ELISA Kit |
PRB-5049-TOTAL |
Cell Biolabs |
96 assays |
EUR 572 |
cDNA from Human Adult Normal Tissue: Brain: Cerebral Cortex |
C1234042-10 |
Biochain |
10 reactions |
EUR 231 |
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes. |
cDNA from Monkey (Cynomolgus) Normal Tissue: Brain: Cerebral Cortex |
C1534042-Cy |
Biochain |
40 reactions |
EUR 376 |
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Frozen Tissue Section - Human Adult Normal: Brain: Cerebral Cortex |
T1234042 |
Biochain |
5 slides |
EUR 349 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
Paraffin Tissue Section - Human Adult Normal: Brain: Cerebral Cortex |
T2234042 |
Biochain |
5 slides |
EUR 211 |
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool. |
Green RNA Lysis Kit 50 |
GREENE1-RNA |
Next Advance |
50pack |
EUR 180 |
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free. |
Green RNA Lysis Kit 250 |
GREENE5-RNA |
Next Advance |
250pack |
EUR 571 |
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free. |
Pink RNA Lysis Kit 50 |
PINKE1-RNA |
Next Advance |
50pack |
EUR 178 |
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
Pink RNA Lysis Kit 250 |
PINKE5-RNA |
Next Advance |
250pack |
EUR 561 |
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
Navy RNA Lysis Kit 50 |
NAVYE1-RNA |
Next Advance |
50pack |
EUR 198 |
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free. |
Navy RNA Lysis Kit 250 |
NAVYE5-RNA |
Next Advance |
250pack |
EUR 651 |
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free. |
Red RNA Lysis Kit 50 |
REDE1-RNA |
Next Advance |
50pack |
EUR 192 |
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
Red RNA Lysis Kit 250 |
REDE5-RNA |
Next Advance |
250pack |
EUR 622 |
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
YELLOW RNA Lysis Kit 50 |
YELLOWE1-RNA |
Next Advance |
50pack |
EUR 192 |
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
YELLOW RNA Lysis Kit 250 |
YELLOWE5-RNA |
Next Advance |
250pack |
EUR 624 |
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
RNA isolater Total RNA Extraction Reagent |
R401-01 |
Vazyme |
100 ml |
EUR 133 |
Total RNA Extraction Kit |
K2014005 |
Biochain |
1 kit |
EUR 344 |
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
Total RNA Isolation Kit |
P-9100 |
EpiGentek |
50 samples |
EUR 347.25 |
Description: The best epigenetics products |
Membrane Protein from Human Adult Normal Tissue: Brain: Cerebral Cortex |
P3234042 |
Biochain |
0.1 mg |
EUR 285 |
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
Cortex |
PC35102 |
Neuromics |
1 Cortical Pair |
EUR 396 |
Cortex |
PC35110 |
Neuromics |
4 million cells |
EUR 866 |
Cortex |
PC35112 |
Neuromics |
4 Cortical Pair |
EUR 1348 |
Cortex |
PC36111 |
Neuromics |
4 Cortical Pair |
EUR 1348 |
5E GREEN RNA Lysis Kit 100 |
GREEN5E100-RNA |
Next Advance |
100pack |
EUR 386 |
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 1000, 5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free. |
5E GREEN RNA Lysis Kit 20 |
GREEN5E20-RNA |
Next Advance |
20pack |
EUR 138 |
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free. |
Green RINO RNA Lysis Kit 50 |
GREENR1-RNA |
Next Advance |
50pack |
EUR 184 |
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with beads. RNase free. |
Green RINO RNA Lysis Kit 250 |
GREENR5-RNA |
Next Advance |
250pack |
EUR 587 |
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with beads. RNase free. |
5E PINK RNA Lysis Kit 100 |
PINK5E100-RNA |
Next Advance |
100pack |
EUR 380 |
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
5E PINK RNA Lysis Kit 20 |
PINK5E20-RNA |
Next Advance |
20pack |
EUR 136 |
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
Pink RINO RNA Lysis Kit 50 |
PINKR1-RNA |
Next Advance |
50pack |
EUR 181 |
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free. |
Pink RINO RNA Lysis Kit 250 |
PINKR5-RNA |
Next Advance |
250pack |
EUR 576 |
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free. |
Navy RINO RNA Lysis Kit 250 |
NAVYR5-RNA |
Next Advance |
250pack |
EUR 666 |
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stainless steel beads. RNase free. |
5E Navy RNA Lysis Kit 100 |
NAVY5E100-RNA |
Next Advance |
100pack |
EUR 453 |
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free. |
5E Navy RNA Lysis Kit 20 |
NAVY5E20-RNA |
Next Advance |
20pack |
EUR 153 |
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free. |
Navy RINO RNA Lysis Kit 50 |
NAVYR1-RNA |
Next Advance |
50pack |
EUR 202 |
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stainless steel beads. RNase free. |
5E RED RNA Lysis Kit 100 |
RED5E100-RNA |
Next Advance |
100pack |
EUR 429 |
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
5E RED RNA Lysis Kit 20 |
RED5E20-RNA |
Next Advance |
20pack |
EUR 148 |
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free. |
Red RINO RNA Lysis Kit 50 |
REDR1-RNA |
Next Advance |
50pack |
EUR 195 |
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free. |
Red RINO RNA Lysis Kit 250 |
REDR5-RNA |
Next Advance |
250pack |
EUR 638 |
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free. |
YELLOW RINO RNA Lysis Kit 50 |
YELLOWR1-RNA |
Next Advance |
50pack |
EUR 199 |
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free. |
YELLOW RINO RNA Lysis Kit 250 |
YELLOWR5-RNA |
Next Advance |
250pack |
EUR 656 |
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free. |
Human Total PSA (t-PSA) ELISA Kit |
PRB-5049-TOTAL-5 |
Cell Biolabs |
5 x 96 assays |
EUR 2283 |
CD1 antibody |
10R-CD1aPGp |
Fitzgerald |
500 ug |
EUR 565 |
Description: Mouse monoclonal CD1 antibody |
Mouse CD1 ELISA Kit |
EMC0864 |
Abclonal |
96Tests |
EUR 521 |
T-cell Surface Glycoprotein CD1 (CD1) Antibody |
abx413840-01mg |
Abbexa |
0.1 mg |
EUR 453 |
|
Total RNA from Mouse Normal Tissue: Adipose |
R1334003-50 |
Biochain |
50 ug |
EUR 214 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Mouse Normal Tissue: Bladder |
R1334010-50 |
Biochain |
50 ug |
EUR 303 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Mouse Normal Tissue: Brain |
R1334035-50 |
Biochain |
50 ug |
EUR 152 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Mouse Normal Tissue: Colon |
R1334090-50 |
Biochain |
50 ug |
EUR 214 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Mouse Normal Tissue: Heart |
R1334122-50 |
Biochain |
50 ug |
EUR 152 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Mouse Normal Tissue: Kidney |
R1334142-50 |
Biochain |
50 ug |
EUR 152 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Mouse Normal Tissue: Liver |
R1334149-50 |
Biochain |
50 ug |
EUR 152 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Mouse Normal Tissue: Lung |
R1334152-50 |
Biochain |
50 ug |
EUR 152 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Mouse Normal Tissue: Pancreas |
R1334188-50 |
Biochain |
50 ug |
EUR 341 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Mouse Normal Tissue: Placenta |
R1334200-50 |
Biochain |
50 ug |
EUR 214 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Mouse Normal Tissue: Rectum |
R1334206-50 |
Biochain |
50 ug |
EUR 214 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Mouse Normal Tissue: Spleen |
R1334246-50 |
Biochain |
50 ug |
EUR 152 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Mouse Normal Tissue: Stomach |
R1334248-50 |
Biochain |
50 ug |
EUR 152 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Mouse Normal Tissue: Testis |
R1334260-50 |
Biochain |
50 ug |
EUR 152 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
AnaPrep Total RNA Extraction Kit |
Z1322015 |
Biochain |
1 kit (48 extractions) Including all required plastic disposables |
EUR 308 |
Description: This kit is developped for our fully automated magnetic bead-based nucleic acid extraction platform which uses preprogrammed protocols and can process up to 12 samples simultaneously. With the AnaPrep 12 Extractor you will have the option to choose and work with a wide range of sample and reagent volumes. This sturdy, realiable and user-friendly machine will save you both time and expenses while ensuring consistently high quality performance and nucleic acids for your downstream applications. |
Total RNA from Lupus: Colon |
R1236090Lup-50 |
Biochain |
50 ug |
EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from hypertension: Heart |
R1236122Hd-2 |
Biochain |
50 ug |
EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Lupus: Kidney |
R1236142Lup-50 |
Biochain |
50 ug |
EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Lupus: Liver |
R1236149Lup-50 |
Biochain |
50 ug |
EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Lupus: Lung |
R1236152Lup-50 |
Biochain |
50 ug |
EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Lupus: Pancreas |
R1236188Lup-50 |
Biochain |
50 ug |
EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Lupus: Spleen |
R1236246Lup-50 |
Biochain |
50 ug |
EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Lupus: Stomach |
R1236248Lup-50 |
Biochain |
50 ug |
EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Lupus: Uterus |
R1236274Lup-50 |
Biochain |
50 ug |
EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA Isolation Kit II |
FATRS--001 |
Favorgen |
100 preps |
EUR 308 |
Total RNA Isolation Kit II |
FATRS--050 |
Favorgen |
50 preps |
EUR 216 |
Total RNA Isolation Kit (Tissue) |
P-9102 |
EpiGentek |
50 samples |
EUR 347.25 |
Description: reagents widely cited |
Total RNA Isolation Kit (Plant) |
P-9104 |
EpiGentek |
50 samples |
EUR 347.25 |
Description: kits suitable for this type of research |
Total RNA ExtractionMini KitAnimal Tissues |
FYG301-50P |
Yeastern Biotech |
50 Preps |
Ask for price |
Total RNA ExtractionMini KitAnimal Tissues |
FYG302-100P |
Yeastern Biotech |
100 Preps |
Ask for price |
Total RNA ExtractionMini KitAnimal Tissues |
FYG302-300P |
Yeastern Biotech |
300 Preps |
Ask for price |
Total RNA ExtractionMini KitPlant Tissues |
FYG303-100P |
Yeastern Biotech |
100 Preps |
Ask for price |
Total RNA ExtractionMini KitPlant Tissues |
FYG303-300P |
Yeastern Biotech |
300 Preps |
Ask for price |
Total RNA ExtractionMini KitPlant Tissues |
FYG303-50P |
Yeastern Biotech |
50 Preps |
Ask for price |
Prefrontal Cortex |
PC35124 |
Neuromics |
Prefrontal Cortex |
EUR 396 |
CD1 antibody (biotin) |
61R-CD1aPGBT |
Fitzgerald |
500 ug |
EUR 543 |
Description: Mouse monoclonal CD1 antibody (biotin) |
CD1 antibody (FITC) |
61R-CD1aPGFT |
Fitzgerald |
500 ug |
EUR 565 |
Description: Mouse monoclonal CD1 antibody (FITC) |
CD1 antibody (PE) |
61R-CD1aPGPE |
Fitzgerald |
100 ug |
EUR 349 |
Description: Mouse monoclonal CD1 antibody (PE) |
anti-CD1 (9H6) |
LF-MA20361 |
Abfrontier |
100 ug |
EUR 354 |
Description: Mouse monoclonal to CD1 |
CD1 Monoclonal Antibody |
ABM40068-003ml |
Abbkine |
0.03ml |
EUR 158 |
|
Description: A monoclonal antibody for detection of CD1 from Human, Mouse, Rat. This CD1 antibody is for IHC-P, IF. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide |
CD1 Monoclonal Antibody |
ABM40068-01ml |
Abbkine |
0.1ml |
EUR 289 |
|
Description: A monoclonal antibody for detection of CD1 from Human, Mouse, Rat. This CD1 antibody is for IHC-P, IF. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide |
CD1 Monoclonal Antibody |
ABM40068-02ml |
Abbkine |
0.2ml |
EUR 414 |
|
Description: A monoclonal antibody for detection of CD1 from Human, Mouse, Rat. This CD1 antibody is for IHC-P, IF. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide |
Anti-CD1 antibody |
STJ96970 |
St John's Laboratory |
200 µl |
EUR 197 |
Description: CD1 is a protein encoded by the CD1A gene which is approximately 37 kDa. CD1 is localised to the cell membrane. It is involved in hematopoietic cell lineage, dendritic cells developmental lineage pathway and the innate immune system. This protein falls under the CD1 family of transmembrane glycoproteins which form heterodimers with beta-2-microglobulin. CD1 mediates the presentation of primarily lipid and glycolipid antigens to T-cells. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. CD1 is expressed in the blood, skin, heart and lymph nodes. Mutations in the CD1A gene may result in myofibroma. STJ96970 was developed from clone 9H6 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous CD1 proteins. |
CD1 Monoclonal Antibody |
EM1068-100ul |
ELK Biotech |
100ul |
EUR 279 |
Description: A Mouse Monoclonal antibody against CD1 from Human/ Rat/ Mouse. This antibody is tested and validated for IHC |
CD1 Monoclonal Antibody |
EM1068-50ul |
ELK Biotech |
50ul |
EUR 207 |
Description: A Mouse Monoclonal antibody against CD1 from Human/ Rat/ Mouse. This antibody is tested and validated for IHC |
Total RNA from Mouse Normal Tissue: Whole Eye |
R1334108-50 |
Biochain |
50 ug |
EUR 296 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Mouse Normal Tissue: Skeletal Muscle |
R1334171-50 |
Biochain |
50 ug |
EUR 152 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Mouse Normal Tissue: Small Intestine |
R1334226-50 |
Biochain |
50 ug |
EUR 214 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Alzheimer's Disease: Brain |
R1236035Alz-50 |
Biochain |
50 ug |
EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Alzheimer's Disease: Pons |
R1236071Alz-10 |
Biochain |
10 ug |
EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Diabetic Disease: Colon |
R1236090Dia-50 |
Biochain |
50 ug |
EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Liver Cirrhosis: Colon |
R1236090Lcs-50 |
Biochain |
50 ug |
EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Diabetic Disease: Esophagus |
R1236106Dia-50 |
Biochain |
50 ug |
EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from hypertension: Interventricular Septum |
R1236130Hd-2 |
Biochain |
50 ug |
EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Liver Cirrhosis: Kidney |
R1236142Lcs-50 |
Biochain |
50 ug |
EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Liver Cirrhosis: Liver |
R1236149Lcs-50 |
Biochain |
50 ug |
EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Liver Cirrhosis: Lung |
R1236152Lcs-50 |
Biochain |
50 ug |
EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Liver Cirrhosis: Diaphragm |
R1236169Lcs-50 |
Biochain |
50 ug |
EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Diabetic Disease: Pancreas |
R1236188Dia-50 |
Biochain |
50 ug |
EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Liver Cirrhosis: Pancreas |
R1236188Lcs-50 |
Biochain |
50 ug |
EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Liver Cirrhosis: Rectum |
R1236206Lcs-50 |
Biochain |
50 ug |
EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Lupus: Small Intestine |
R1236226Lup-50 |
Biochain |
50 ug |
EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Liver Cirrhosis: Spleen |
R1236246Lcs-50 |
Biochain |
50 ug |
EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Total RNA from Diabetic Disease: Stomach |
R1236248Dia-50 |
Biochain |
50 ug |
EUR 351 |
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes. |
Broad Range Total RNA Isolation Kit |
K1341050 |
Biochain |
1 kit |
EUR 266 |
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation. |
Plant Total RNA Mini Kit (50prep) |
FAPRK-001 |
Favorgen |
50 preps |
EUR 165 |
However, the supply of nucleic acids to the central nervous system (CNS), in specific by the systemic route, stays a main hurdle. This assessment will concentrate on the methods for systemic supply of therapeutic nucleic acids designed to beat these boundaries. Pathways and mechanisms of transport throughout the blood-brain barrier which might be exploited for supply are described, focusing in specific on smaller nucleic acids together with antisense oligonucleotides (ASOs) and small interfering RNA (siRNA).